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In a subsequent analysis of data from this trial, the septic patients that were given parenteral thiamin (n=31) had lower creatinine concentrations throughout the treatment and were less likely to need renal replacement therapy compared to placebo (n=39

Disadvantages: Must be handled with dry hands, cannot be split or crushed, must remain in original packaging until use, limited dose flexibility

PMID: 35 GaoS.GaoY.CaiL.QinR

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